The pharmacodynamics of cocaine require the complicated relationships of neurotransmitters (inhibiting monoamine uptake in rats with ratios of about: serotonin:dopamine = two:three, serotonin:norepinephrine = 2:5).[109][fifteen] The most thoroughly studied impact of cocaine about the central anxious system is definitely the blockade of the dopamine

Crack cocaine is called “crack” because of the crackling Seems it helps make when heated. Coca leaves are usually combined with an alkaline compound (including lime) and chewed into a wad that's retained from the mouth concerning gum and cheek and sucked of its juices. People today snort powder cocaine from the nose, others rub it into their

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